Institut des Sciences Moléculaires d'Orsay



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Accueil > Séminaires > Année 2017 > Séminaire de Masaaki Fujii (26 octobre 2017)

Séminaire de Masaaki Fujii (26 octobre 2017)

Laboratory for Chemistry and Life Science, Institute of Innovative Research Tokyo Institute of Technology

par Martrenchard-Barra Séverine - 5 octobre 2017

Electrosplay / cold ion trap laser spectroscopy on biomolecules
Bottom-up approach to molecular recognition in biological systems

Receptor-neurotransmitter molecular recognition is key of
neurotransmission. Here, we measured ultraviolet and infrared spectra of
complexes between a partial peptide SIVSF (Ser-Ile-Val-Ser-Phe), the binding motif of a catechol ring in the adrenergic receptor, and various ligands such as
adrenaline, noradrenaline and dopamine. The secondary structures of
SIVSF in the complexes are assigned and the relation to the molecular
recognition mechanism will be discussed.

Séminaire de M. Fujii - 130.5 ko

26 octobre 2017