ISMO

Institut des Sciences Moléculaires d'Orsay


Partenaires

CNRS UPS




Thursday 28 March


Site update
Wednesday 20 March


Home > Platforms > Le Centre de Photonique pour la biologie et les matériaux (CPBM)

Le Centre de Photonique pour la biologie et les matériaux (CPBM)

Resources are available for reservation after training.

CPBM : Centre de Photonique pour la Biologie et les Matériaux

The Centre de Photonique pour la biologie et les matériaux (CPBM) is a fluorescence dynamics imaging technology facility open to both academic and industrial users. CPBM promotes the interaction of various scientific communities: physics, chemistry, biology, medicine; and accelerates the transfer of technology.
The entire research activity of the center is structured around two main themes: Multimodal fluorescence imaging for biological, environmental and materials applications (…)

Read more

Cell Culture

The facility allows to prepare a wide variety of biological samples on site and makes possible studies in the living environment.
Biosafety level 2 laboratories The cell culture laboratory is confined and labeled BSL2 for the cells culture and level 2 pathogens. It has two rooms, which allow on one side the culture of eukaryotic cells (level 2 cell lines, primary culture, etc.) , and on the other the preparation of bacterial samples. It is equipped, for the eukaryotic part, with a PSM, (…)

Read more

IDEFIX : imaging the dynamics of fluorescence emission by two-photon excitation

FLIM, FCS and FCCS Biphotonic experiment

Thanks to a synergy of skills, the Laboratoire de Photophysique Moléculaire, the Laboratorie Charles Fabry of Institut d’Optique and the Laboratoire de Chimie Physique have developed an original device for imaging the dynamics of fluorescence emission by two-photon excitation (I.D.E.F.I.X.).
The IDEFIX microscope accessible at CPBM allows an analysis of the fluorescence emitted by the constituents of the sample or by the chromophores diffusing or present in the sample, thanks to the (…)

Read more

E AFM TIRF

The developpement of the set up will be put on the improvement of the method of measurement of local electric charges and ionic transfers by an electro-mechanical AFM mode –EMSM- (Nanoscale, 2015, 7, 8843, an in vivo study of electrical charge distribution on the bacterial cell wall by AFM in vibrating force mode). The main aims will be: (i) the characterization of the local heterogeneities of membrane’s surface charges and their temporal changes during the modification of the contact interface between bacteria and the solid surface as studied by TIRF; (ii) the study of cross-linked coupling between physicochemical properties of membranes and cellular metabolism during colonization of the solid surface by bacteria and formation of bacterial network: aggregates, biofilms.

Read more

Publications

Publications (2015-2022) « Space-selective creation of photonics functions in a new organic material: Femtosecond laser direct writing in Zeonex glass of refractive index change and photoluminescence ». Que Ruyue, Houel-Renault Ludivine, Temagoult Mebarek, Herrero Christian, Lancry Matthieu, and Poumellec Bertrand. Optical Materials (2022), 15. https://doi.org/10.1016/j.optmat.2022.112651. « Luminescence-Sensitive Surfaces Bearing Ratiometric Nanoparticles for Bacteria Growth Detection (…)

Read more