Accueil > Équipes scientifiques > Structure et dynamique des systèmes complexes isolés photoexcités (SYSIPHE) > MEcanismes MOléculaires d’espèces biomimétiques (MEMO) > Offres de stages, thèses et post-docs > Vaporization of neutral biomolecules assisted by supercritical CO2 for a structural characterization by conformer-resolved laser spectroscopy
Master 2 Internship Physical Chemistry
Vaporization of neutral biomolecules assisted by supercritical CO2 for a structural characterization by conformer-resolved laser spectroscopy
Master 2 Internship
par - 18 septembre 2023 (modifié le 19 septembre 2023)
Contact : Eric Gloaguen
Phone : 01 69 15 76 78
Dates : February – July 2024
Research Laboratory : Institut des Sciences Moléculaires d’Orsay (ISMO), Université Paris Saclay, Bâtiment 520, Orsay
Supervisor :
GLOAGUEN Eric
CNRS Researcher
Vaporization of a liquid or solid sample opens the way to numerous techniques (mass spectrometry, resolved spectroscopies), and is an important step in the analysis of biomolecules. Introducing neutral systems in the gas phase may however be tricky for fragile molecules for which the existing techniques (heating, laser desorption) only suit the most simple systems. In this context, the intern will work on a new vaporization technique based on the dissolution of biomolecules into supercritical CO2. Applied to small peptides and sugars, this technique aims at characterizing the structure of isolated systems by means of conformer-resolved IR and UV laser spectroscopy, interpreted by quantum chemistry calculations. The intern will have the opportunity to work on both experimental and theoretical aspects of the larger ANR-funded collaborative project VAPOBIO. She/He will work together with a PhD student within the team “Structure et dynamique des systèmes complexes isolés photoexcités” (SYSIPHE) located at Institut des Sciences Moléculaires d’Orsay (ISMO). This internship may be followed by an application to a PhD thesis in the group in the fall of 2024.
Voir en ligne : MEcanismes MOléculaires d’espèces biomimétiques (MEMO)
Dans la même rubrique :
- Vaporization of neutral biomolecules assisted by supercritical CO2 for a structural characterization by conformer-resolved laser spectroscopy
- Investigation of Stark effects in isolated molecular ion pairs
- Caractérisation des propriétés structurales et électroniques de systèmes moléculaires isolés par spectroscopies laser en champ électrique intense