ISMO

Institut des Sciences Moléculaires d'Orsay


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jeudi 20 juin


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mercredi 19 juin


Accueil > Équipes scientifiques > Nanomédecine et Biophotonique (NanoBio) > Nanoparticules de type "cage" pour lutter contre des maladies sévères > Publications

Publications

2021

Chaupard, M., de Frutos, M., & Gref, R. (2021). Deciphering the Structure and Chemical Composition of Drug Nanocarriers: From Bulk Approaches to Individual Nanoparticle Characterization. Part. Part. Syst. Charact., .
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Christodoulou I, B. T., Li X, Patriarche G, Serre C, Marlière C, Gref R. (2021). Degradation Mechanism of Porous Metal-Organic Frameworks by In Situ Atomic Force Microscopy. Nanomaterials (Basel), 11(3), 722.
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Li, X., Porcino, M., Qiu, J., Constantin, D., Martineau-Corcos, C., & Gref, R. (2021). Doxorubicin-Loaded Metal-Organic Frameworks Nanoparticles with Engineered Cyclodextrin Coatings: Insights on Drug Location by Solid State NMR Spectroscopy. Nanomaterials (Basel), 11(4), 945.
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Porcino M, Li, X., Gref R, & Martineau-Corcos C. (2021). Solid-State NMR Spectroscopy: A Key Tool to Unravel the Supramolecular Structure of Drug Delivery Systems..
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Porcino, M., Li, X., Gref, R., & Martineau-Corcos C. (2021). Solid-state NMR spectroscopy as a powerful tool to investigate the location of fluorinated lipids in highly porous hybrid organic-inorganic nanoparticles. Magn Reson Chem, .
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Siyu He, L. W., Xue Li, Hongyu Sun, Ting Xiong, Jie Liu, Chengxi Huang, Huipeng Xu, Huimin Sun, Weidong Chen, Ruxandra Gref, Jiwen Zhang. (2021). Metal-organic frameworks for advanced drug delivery..
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2020

Gref, R., Delomenie C, Maksimenko A, Gouadon E, Percoco, G., Lati E, Desmaele, D., Zouhiri, F., & Couvreur P. (2020). Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin. (Vol. 10).
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I Christodoulou, C. S., R Gref. (2020). Metal-organic frameworks for drug delivery: Degradation mechanism and in vivo fate. In Metal-Organic Frameworks for Biomedical Applications (pp. 467–489).
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Kena Zhao, T. G., Caifen Wang, Yong Zhou, Ting Xiong, Li Wu, Xue Li, Priyanka Mittal, Senlin Shi, Ruxandra Gref. (2020). Glycoside scutellarin enhanced CD-MOF anchoring for laryngeal delivery. Acta Pharm Sin B, 10(9), 1709.
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Li X, Porcel, E., Menendez-Miranda, M., Qiu, J., Yang, X., Serre, C., Pastor, A., Desmaele, D., Lacombe S, & Gref, R. (2020). Highly Porous Hybrid Metal-Organic Nanoparticles Loaded with Gemcitabine Monophosphate: a Multimodal Approach to Improve Chemo- and Radiotherapy. (Vol. 15).
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Li, X., Porcino, M., Martineau-Corcos, C., Guo, T., Xiong, T., Zhu, W. F., Patriarche, G., Pechoux, C., Perronne, B., Hassan, A., Kummerle, R., Michelet, A., Zehnacker-Rentien, A., Zhang, J. W., & Gref, R. (2020). Efficient incorporation and protection of lansoprazole in cyclodextrin metal-organic frameworks. International Journal of Pharmaceutics, 585, 119442.
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Li, X., Salzano, G., Qiu, J., Menard, M., Berg, K., Theodossiou, T., Ladaviere, C., & Gref, R. (2020). Drug-Loaded Lipid-Coated Hybrid Organic-Inorganic “Stealth” Nanoparticles for Cancer Therapy. Front Bioeng Biotechnol, .
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Villemagne, B., Machelart A, Tran, N. C., Flipo M, Moune, M., Leroux F, Piveteau, C., Wohlkonig A, Wintjens, R., Li X, Gref R, Brodin P, Deprez, B., Baulard AR, & Willand, N. (2020). Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity. (Vol. 6).
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2019

Perez-Lloret M, Fraix A, Petralia S, Conoci, S., Tafani V, Cutrone, G., Vargas-Berenguel, A., Gref R, & Sortino S. (2019). One-Step Photochemical Green Synthesis of Water-Dispersible Ag, Au, and Au@Ag Core-Shell Nanoparticles. Chemistry, 25(64), 14638.
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Cutrone G, Q. J., Menendez-Miranda M, Casas-Solvas JM, Aykaç A, Li X, Foulkes D, Moreira-Alvarez B, Encinar JR, Ladavière C, Desmaële D, Vargas-Berenguel A, Gref R. (2019). Comb-like dextran copolymers: A versatile strategy to coat highly porous MOF nanoparticles with a PEG shell. Carbohydr Polym, 223, 115085.
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Jain-Beuguel C, Li, X., Houel-Renault, L., Modjinou T, Gref R, Renard, E., & Langlois V. (2019). Water-Soluble Poly(3-hydroxyalkanoate) Sulfonate: Versatile Biomaterials Used as Coatings for Highly Porous Nano-Metal Organic Framework. (Vol. 20).
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Jain-Beuguel, C., Li, X., Houel-Renault, L., Modjinou, T., Simon-Colin, C., Gref, R., Renard E, & Langlois V. (2019). Water-Soluble Poly(3-hydroxyalkanoate) Sulfonate: Versatile Biomaterials Used as Coatings for Highly Porous Nano-Metal Organic Framework. (Vol. 20).
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Jian Xu, L. W., Tao Guo, Guoqing Zhang, Caifen Wang, Haiyan Li, Xue Li, Vikramjeet Singh, Weidong Chen, Ruxandra Gref, Jiwen Zhang. (2019). A “Ship-in-a-Bottle” strategy to create folic acid nanoclusters inside the nanocages of gamma-cyclodextrin metal-organic frameworks. Int J Pharm, 556, 89.
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Li, X., Semiramoth, N., Hall, S., Tafani, V., Josse, J., Laurent, F., Salzano, G., Foulkes, D., Brodin, P., Majlessi, L., Ghermani, N. ‐E., Maurin, G., Couvreur, P., Serre, C., Bernet‐Camard, M. ‐F., Zhang, J., & Gref, R. (2019). Combinatorial Drug Therapy: Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections (Part. Part. Syst. Charact. 3/2019). Part. Part. Syst. Charact., 36(3), 1970009.
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Li, X., Semiramoth, N., Hall, S., Tafani, V., Josse, J., Laurent, F., Salzano, G., Foulkes, D., Brodin, P., Majlessi, L., Ghermani, N. ‐E., Maurin, G., Couvreur, P., Serre, C., Bernet‐Camard, M. ‐F., Zhang, J., & Gref, R. (2019). Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections. Part. Part. Syst. Charact., 36(3), 1800360.
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Pastor A,, Machelart A,, Li X,, Willand N,., Baulard A, Brodin, P., Gref R, & Desmaele D. (2019). A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation. (Vol. 17).
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Porcino, M., Christodoulou, I., Vuong, M. D. L., Gref, R., & Martineau-Corcos, C. (2019). New insights on the supramolecular structure of highly porous core–shell drug nanocarriers using solid-state NMR spectroscopy. RSC Adv., 9(56), 89.
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Shailendra Shakya, Y. H., Xiaohong Ren, Tao Guo, Abi Maharjan, Ting Luo, Tingting Wang, Ramesh Dhakhwa, Balmukunda Regmi, Haiyan Li, Ruxandra Gref, Jiwen Zhang. (2019). Ultrafine Silver Nanoparticles Embedded in Cyclodextrin Metal-Organic Frameworks with GRGDS Functionalization to Promote Antibacterial and Wound Healing Application. (Vol. 15).
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Yuanzhi He, W. Z., Tao Guo, Guoqing Zhang, Wei Qin, Liu Zhang, Caifen Wang, Weifeng Zhu, Ming Yang, Xiaoxiao Hu, Vikramjeet Singh, Li Wu, Ruxandra Gref, Jiwen Zhang. (2019). Drug nanoclusters formed in confined nano-cages of CD-MOF: dramatic enhancement of solubility and bioavailability of azilsartan. Acta Pharm Sin B, 9(1), 97.
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2017

Aykac, A., Noiray, M., Malanga, M., Agostoni, V., Casas-Solvas, J. M., Fenyvesi, E., Gref, R., & Vargas-Berenguel, A. (2017). A non-covalent “click chemistry” strategy to efficiently coat highly porous MOF nanoparticles with a stable polymeric shell. Biochimica Et Biophysica Acta-General Subjects, 1861(6), 1606–1616.
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Costa-Gouveia, J., Pancani, E., Jouny, S., Machelart, A., Delorme, V., Salzano, G., Iantomasi, R., Piveteau, C., Queval, C. J., Song, O. R., Flipo, M., Deprez, B., Saint-Andre, J. P., Hureaux, J., Majlessi, L., Willand, N., Baulard, A., Brodin, P., & Gref, R. (2017). Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles. Scientific Reports, 7, 5390.
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Feng, X. R., Ding, J. X., Gref, R., & Chen, X. S. (2017). Poly(beta-cyclodextrin)-mediated polylactide-cholesterol stereocomplex micelles for controlled drug delivery. Chinese Journal Of Polymer Science, 35(6), 693–699.
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Gref, R., Couvreur, P., & Loftsson, T. (2017). Editorial Special edition of International Journal of Pharmaceutics in honor of Professor Dominique Duchene. International Journal Of Pharmaceutics, 531(2), 411–412.
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Li, H. Y., Lv, N. N., Li, X., Liu, B. T., Feng, J., Ren, X. H., Guo, T., Chen, D. W., Stoddart, J. F., Gref, R., & Zhang, J. W. (2017). Composite CD-MOF nanocrystals-containing microspheres for sustained drug delivery. Nanoscale, 9(22), 7454–7463.
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Li, X., Guo, T., Lachmanski, L., Manoli, F., Menendez-Miranda, M., Manet, I., Guo, Z., Wu, L., Zhang, J. W., & Gref, R. (2017). Cyclodextrin-based metal-organic frameworks particles as efficient carriers for lansoprazole: Study of morphology and chemical composition of individual particles. International Journal Of Pharmaceutics, 531(2), 424–432.
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Li, X., Lachmanski, L., Safi, S., Sene, S., Serre, C., Greneche, J. M., Zhang, J., & Gref, R. (2017). New insights into the degradation mechanism of metal-organic frameworks drug carriers. Scientific Reports, 7, 13142.
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Li, X., Salzano, G., Zhang, J. W., & Gref, R. (2017). Spontaneous Self-Assembly of Polymeric Nanoparticles in Aqueous Media: New Insights From Microfluidics, In Situ Size Measurements, and Individual Particle Tracking. Journal Of Pharmaceutical Sciences, 106(1), 395–401.
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Lv, N. N., Guo, T., Liu, B. T., Wang, C. F., Singh, V., Xu, X. N., Li, X., Chen, D. W., Gref, R., & Zhang, J. W. (2017). Improvement in Thermal Stability of Sucralose by Y-Cyclodextrin Metal-Organic Frameworks. Pharmaceutical Research, 34(2), 269–278.
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Marcos-Almaraz, M. T., Gref, R., Agostoni, V., Kreuz, C., Clayette, P., Serre, C., Couvreur, P., & Horcajada, P. (2017). Towards improved HIV-microbicide activity through the co-encapsulation of NRTI drugs in biocompatible metal organic framework nanocarriers. Journal Of Materials Chemistry B, 5(43), 8563–8569.
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Ortega, J. M., Glotin, F., Prazeres, R., Li, X., & Gref, R. (2017). Far infrared micro-spectroscopy: an innovative method to detect individual metal-organic framework particles. Applied Optics, 56(23), 6663–6667.
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Rodriguez-Ruiz, V., Maksimenko, A., Salzano, G., Lampropoulou, M., Lazarou, Y. G., Agostoni, V., Couvreur, P., Gref, R., & Yannakopoulou, K. (2017). Positively charged cyclodextrins as effective molecular transporters of active phosphorylated forms of gemcitabine into cancer cells. Scientific Reports, 7, 8353.
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Salzano, G., Wankar, J., Ottani, S., Villemagne, B., Baulard, A. R., Willand, N., Brodin, P., Manet, I., & Gref, R. (2017). Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs. International Journal Of Pharmaceutics, 531(2), 577–587.
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Simon-Yarza, T., Gimenez-Marques, M., Mrimi, R., Mielcarek, A., Gref, R., Horcajada, P., Serre, C., & Couvreur, P. (2017). A Smart Metal-Organic Framework Nanomaterial for Lung Targeting. Angewandte Chemie-International Edition, 56(49), 15565–15569.
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Singh, V., Guo, T., Wu, L., Xu, J. H., Liu, B. T., Gref, R., & Zhang, J. W. (2017). Template-directed synthesis of a cubic cyclodextrin polymer with aligned channels and enhanced drug payload. Rsc Advances, 7(34), 20789–20794.
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Singh, V., Guo, T., Xu, H. T., Wu, L., Gu, J. K., Wu, C. B., Gref, R., & Zhang, J. W. (2017). Moisture resistant and biofriendly CD-MOF nanoparticles obtained via cholesterol shielding. Chemical Communications, 53(66), 9246–9249.
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Singh, V., Xu, J. H., Wu, L., Liu, B. T., Guo, T., Guo, Z., York, P., Gref, R., & Zhang, J. W. (2017). Ordered and disordered cyclodextrin nanosponges with diverse physicochemical properties. Rsc Advances, 7(38), 23759–23764.
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Wankar, J., Salzano, G., Pancani, E., Benkovics, G., Malanga, M., Manoli, F., Gref, R., Fenyvesi, E., & Manet, I. (2017). Efficient loading of ethionamide in cyclodextrin-based carriers offers enhanced solubility and inhibition of drug crystallization. International Journal Of Pharmaceutics, 531(2), 568–576.
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Xu, X. N., Wang, C. F., Li, H. Y., Li, X., Liu, B. T., Singh, V. J., Wang, S. X., Sun, L. X., Gref, R. X., & Zhang, J. W. (2017). Evaluation of drug loading capabilities of gamma-cyclodextrin-metal organic frameworks by high performance liquid chromatography. Journal Of Chromatography A, 1488, 37–44.
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2016

Conte, C., Fotticchia, I., Tirino, P., Moret, F., Pagano, B., Gref, R., Ungaro, F., Reddi, E., Giancola, C., & Quaglia, F. (2016). Cyclodextrin-assisted assembly of PEGylated polyester nanoparticles decorated with folate. Colloids And Surfaces B-Biointerfaces, 141, 148–157.
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Ding, J. X., Cheng, Y. L., Li, M. Q., Gref, R., & Chen, X. S. (2016). Smart Polymeric Nanocarriers. Journal Of Nanomaterials, .
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Duchene, D., & Gref, R. (2016). Small is beautiful: Surprising nanoparticles. International Journal Of Pharmaceutics, 502(1-2), 219–231.
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Duchene, D., Cavalli, R., & Gref, R. (2016). Cyclodextrin-based Polymeric Nanoparticles as Efficient Carriers for Anticancer Drugs. Current Pharmaceutical Biotechnology, 17(3), 248–255.
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Liu, B. T., Li, H. Y., Xu, X. N., Li, X., Lv, N. N., Singh, V., Stoddart, J. F., York, P., Xu, X., Gref, R., & Zhang, J. W. (2016). Optimized synthesis and crystalline stability of gamma-cyclodextrin metal-organic frameworks for drug adsorption. International Journal Of Pharmaceutics, 514(1), 212–219.
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Simon-Yarza, M. T., Baati, T., Paci, A., Lesueur, L. L., Seck, A., Chiper, M., Gref, R., Serre, C., Couvreur, P., & Horcajada, P. (2016). Antineoplastic busulfan encapsulated in a metal organic framework nanocarrier: first in vivo results. Journal Of Materials Chemistry B, 4(4), 585–588.
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Simon-Yarza, T., Baati, T., Neffati, F., Njim, L., Couvreur, P., Serre, C., Gref, R., Najjar, M. F., Zakhama, A., & Horcajada, P. (2016). In vivo behavior of MIL-100 nanoparticles at early times after intravenous administration. International Journal Of Pharmaceutics, 511(2), 1042–1047.
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2015

Abed, N., Said-Hassane, F., Zouhiri, F., Mougin, J., Nicolas, V., Desmaele, D., Gref, R., & Couvreur, P. (2015). An efficient system for intracellular delivery of beta-lactam antibiotics to overcome bacterial resistance. Scientific Reports, 5.
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Agostoni, V., Horcajada, P., Noiray, M., Malanga, M., Aykac, A., Jicsinszky, L., Vargas-Berenguel, A., Semiramoth, N., Daoud-Mahammed, S., Nicolas, V., Martineau, C., Taulelle, F., Vigneron, J., Etcheberry, A., Serre, C., & Gref, R. (2015). A “green” strategy to construct non-covalent, stable and bioactive coatings on porous MOF nanoparticles. Scientific Reports, 5, 7925.
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Fraix, A., Kandoth, N., Gref, R., & Sortino, S. (2015). A Multicomponent Gel for Nitric Oxide Photorelease with Fluorescence Reporting. Asian Journal Of Organic Chemistry, 4(3), 256–261.
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Ladaviere, C., & Gref, R. (2015). Toward an optimized treatment of intracellular bacterial infections: input of nanoparticulate drug delivery systems. Nanomedicine, 10(19), 3033–3055.
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Nie, S. Y., Zhang, X. F., Gref, R., Couvreur, P., Qian, Y., & Zhang, L. J. (2015). Multilamellar Nanoparticles Self-Assembled from Opposite Charged Blends: Insights from Mesoscopic Simulation. Journal Of Physical Chemistry C, 119(35), 20649–20661.
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Ralay-Ranaivo, B., Borgel, D., Couvreur, P., & Gref, R. (2015). Trends in the development of oral anticoagulants. Therapeutic Delivery, 6(6), 685–703.
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Rodriguez-Ruiz, V., Maksimenko, A., Anand, R., Monti, S., Agostoni, V., Couvreur, P., Lampropoulou, M., Yannakopoulou, K., & Gref, R. (2015). Efficient “green” encapsulation of a highly hydrophilic anticancer drug in metal-organic framework nanoparticles. Journal Of Drug Targeting, 23(7-8), 759–767.
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2014

Deshayes, S., & Gref, R. (2014). Synthetic and bioinspired cage nanoparticles for drug delivery. Nanomedicine, 9(10), 1545–1564.
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Ralay-Ranaivo, B., Desmaele, D., Bianchini, E. P., Lepeltier, E., Bourgaux, C., Borgel, D., Pouget, T., Tranchant, J. F., Couvreur, P., & Gref, R. (2014). Novel self assembling nanoparticles for the oral administration of fondaparinux: Synthesis, characterization and in vivo evaluation. Journal Of Controlled Release, 194, 323–331.
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