
One of the vocations of theInstitut des Sciences Moléculaires d’Orsay is the experimental and theoretical study of processes resulting from the interaction of sources with molecular species. For these purposes, the Institute has instrumentation enabling the synthesis and detection of various molecular species. The experimental techniques used are: fluorescence collection, mass spectrometry, photoelectron spectroscopy, STM microscopy, fluorescence microscopy and various non-linear optical techniques.
Implementing these instruments requires a wide range of specialist skills, including laser optics, spectroscopy, cryogenics, vacuum techniques, detection and chemistry. These skills are brought together in a 10-strong support team organised into a “Scientific Instrumentation” department.
Responsibilities:
Project development and studies in the fields of optics, chemistry, vacuum/cryogenics and measurement.
Technical assistance to experimental teams in the above-mentioned fields.
Management of the Institute’s laser equipment.
Preparing purchasing dossiers.
Advice on orders and centralisation.
Management of dyes and alcohols.
Hosting trainees.
Management of the Institute’s vacuum and cryogenics components.
Management of the chemistry characterisation platform.
Expertises :
Optics
Laser
Detection
Mechanics
Spectroscopy
Cryogenics
Vacuum technology
Chemistry
Physico-chemical characterisation

Mechanistic and Structural Characterization of Organometallic and Biochemical Systems using Advanced Mass Spectrometry
Mechanistic and Structural Characterization of Organometallic and Biochemical Systems using Advanced Mass Spectrometry
Mechanistic and Structural Characterization of Organometallic and Biochemical Systems using Advanced Mass Spectrometry
Lyna Bourehil
Department of Chemistry and Applied Biosciences, ETH Zurich
Vibrational and electronic dynamics of large molecular systems
This research activity focuses on resolving the fundamental physical and chemical processes at work in medium- to large-scale molecular systems, whether in the gas or condensed phase, using atomic simulations and dedicated experiments such as infrared emission monitoring of isolated molecules. The systems studied range from isolated hydrocarbon molecules to clusters or biomolecules. Key problems such as the dynamics of carbonaceous molecules in the interstellar medium or the ultra-fast dynamics of biomolecules are addressed. Our simulations are directly motivated by […]
Quantum Metrology
La physique moléculaire ultrafroide en microgravité, dans un environnement spatial, offre de nouvelles perspectives passionnantes pour explorer de nouveaux régimes de physique moléculaire à très basse énergie, offrant ainsi la possibilité de concevoir de nouveaux types d'interféromètres à ondes de matière. Ces avancées sont cruciales pour les mesures de précision en physique fondamentale et en physique des systèmes à N-corps [1]. En effet, l'émergence du refroidissement et du piégeage d'atomes par laser, suivis de la création de condensats de Bose-Einstein, a [...]
Photoinduced Dynamics
I am text block. Click edit button to change this text. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo. Time-resolved spectroscopy of unimolecular dynamics The dynamics of a chemical reaction is an essential information that must be obtained to obtain a detailed vision of the mechanism of that reaction. The chemical phenomenon studied is photoinduced by a laser. This excitation occurs without geometric change of the reactive system, but the [...]
4th session of the Saclay Plateau Ultra-Fast Community Forum (FOCUS)
June 12, 2025 at the École Polytechnique
The goal of FOCUS is to federate the plateau de Saclay’s community (IP-Paris & Université Paris-Saclay) that work on scientific subjects dealing with (almost) ultrafast dynamics.
FOCUS is a local and convivial meeting opportunity, encouraging discussions and scientific encounters.
SYSTEMAE team members
Permanent staff: Hervé BERGERON Associate Professor Séverine BOYÉ-PÉRONNE Professor +33(0)1.69.15.63.07 Laurent COUDERT Research Director +33(0)1.69.15.41.56 Emmanuel DARTOIS Research Director +33(0)1.69.85.85.27 Stéphane DOUIN Associate Professor +33(0)1.69.15.72.42 Cyril FALVO Associate Professor Bérenger GANS Researcher +33(0)1.69.15.82.56 Marie GODARD Associate Professor +33(0)1.69.15.38.86 Minh Huong HA THI Associate Professor +33(0)1.69.15.38.86 Ugo JACOVELLA Researcher +33(0)1.69.15.44.83 Marion JACQUEY Associate Professor Marie-Aline MARTIN-DRUMEL Researcher +33(0)1.69.15.44.83 Rachel MÉALLET Professor +33(0)1.69.15.31.28 Sabine MORISSET Researcher +33(0)1.69.15.78.63 Pascal PARNEIX Professor [...]

Proof of concept for the combination of Gemcitabine-loaded MOF and hadrontherapy to treat hypoxic cancers
Proof of concept for the combination of Gemcitabine-loaded MOF and hadrontherapy to treat hypoxic cancers
In a study published in the International Journal of Pharmaceutics, ISMO researchers have published the first study of an innovative strategy that combines porous organometallic nanoparticles (nanoMOFs) loaded with the anti-cancer drug Gemcitabine monophosphate (GemMP) and helium and carbon ion hadrontherapy.